منابع مشابه
Translational Control across Eukaryotes
Diversity is one of the most significant features of life. The current assessment of biodiversity on Earth reaches several millions of living species, and an unimaginable number of species that have gone extinct. Further more, diversity is ingrained in all aspects of life, namely, genetics, metabolic needs, cell complexity, body plans and organismal morphology , developmental programs, behavior...
متن کاملFrom factors to mechanisms: translation and translational control in eukaryotes.
Biochemical and genetic studies are revealing a network of interactions between eukaryotic translation initiation factors, further refining or redefining perceptions of their function. The notion of translated mRNA as a 'closed-loop' has gained support from the identification of physical and functional interactions between the two mRNA ends and their associated factors. Translational control me...
متن کاملTranslational control of viral gene expression in eukaryotes.
As obligate intracellular parasites, viruses rely exclusively on the translational machinery of the host cell for the synthesis of viral proteins. This relationship has imposed numerous challenges on both the infecting virus and the host cell. Importantly, viruses must compete with the endogenous transcripts of the host cell for the translation of viral mRNA. Eukaryotic viruses have thus evolve...
متن کاملDyneins Across Eukaryotes: A Comparative Genomic Analysis
Dyneins are large minus-end-directed microtubule motors. Each dynein contains at least one dynein heavy chain (DHC) and a variable number of intermediate chains (IC), light intermediate chains (LIC) and light chains (LC). Here, we used genome sequence data from 24 diverse eukaryotes to assess the distribution of DHCs, ICs, LICs and LCs across Eukaryota. Phylogenetic inference identified nine DH...
متن کاملSignal recognition particle mediates post-translational targeting in eukaryotes.
Signal recognition particle (SRP) plays a central role in the delivery of classical secretory and membrane proteins to the endoplasmic reticulum (ER). All nascent chains studied to date dissociate from SRP once released from the ribosome, thereby supporting a strictly cotranslational mode of action for eukaryotic SRP. We now report a novel post-translational function for SRP in the targeting of...
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ژورنال
عنوان ژورنال: Comparative and Functional Genomics
سال: 2012
ISSN: 1531-6912,1532-6268
DOI: 10.1155/2012/317690